研发团队社会资本对创新绩效作用路径——心理安全和学习行为整合视角

一方面,研发团队作为企业创新活动的基本单位,对提升企业创新能力起着关键作用;另一方面,如何有效管理研发团队以促进创新,在现实中又面临严峻挑战.基于团队心理安全和学习行为整合视角,以151个研发团队585个研发成员为样本,实证研究研发团队社会资本对创新绩效的作用路径.研究结果表明:研发团队3维社会资本(结构、认知和关系)对创新绩效均具有显著的积极影响,团队学习行为部分中介团队心理安全与创新绩效的关系;团队心理安全部分中介团队社会资本与学习行为的关系;团队心理安全和学习行为分别部分中介团队结构资本、认知资本与创新绩效的关系,完全中介团队关系资本与创新绩效的关系.     

“区块链+国家审计”助力大数据反腐研究

巩固发展反腐败斗争压倒性胜利,应重视发挥国家审计的腐败预防、揭示和抵御作用。区块链是信息技术革命中的一项创新性技术,能够以其体系去中心化、交易机制透明、数据不可篡改等核心特征,应对大数据反腐所面临的现实困境。通过体系去中心化促进信息共享,交易机制透明性缓解信息不对称,数据不可篡改性保证信息真实。区块链技术与国家审计相结合,能够突破数据壁垒、推动反腐协作,促进信息透明、揭示隐性腐败,保障信息真实、强化审计问责,从而进一步提升大数据反腐的效率与效果。立足于中国特色“审计智能+”建设背景,我国应以区块链为底层技术打造新型数字化审计平台,克服大数据反腐应用中的侵犯个人隐私、数据壁垒、信息失真等问题,在完善制度化反腐防腐协同机制的基础上,开创“制度+科技”反腐防腐的新局面。     

铁路安全的行政法规制:经验与借鉴

面对迅速发展的铁路运输事业,中国铁路安全法律制度还存在一些不足,亟需完善。美国联邦铁路安全法律制度在改善其铁路安全状况方面发挥了重要作用。它的主要特点是:明确安全为最高优先事项、重视铁路安全规制机构的建设、运用多元的规制工具和执行手段、设置必要的行政程序。美国经验对我国完善铁路安全立法、加强铁路安全行政组织建设、优化行政行为形式和改进行政程序具有借鉴价值。     

Recent changes in FDA's good laboratory practice regulations

In the Federal Register of December 22, 1978, the Food and Drug Administration (FDA) published regulations which described Good Laboratory Practice for safety tests conducted on regulated products (Anonymous, 1978). The regulations, popularly known as GLPs, have become universally recognized as the basic criteria for the conduct of a valid safety test and for assuring the quality and integrity of the collected data. Along with the publication of the GLPs, FDA instituted a vigorous program of inspection of toxicology laboratories to determine the degree of adherence to the regulations. In 1984, based on inspectional findings which revealed that a large majority of toxicology laboratories were adhering to the GLPs, FDA published a proposal intended to reduce the burden of compliance with the regulations (Anonymous, 1984). The proposal outlined major changes in the provisions on quality assurance, protocol preparation, test and control article characterization, and retention of specimens and samples. The final order based on the proposal was published in the federal register of September 4, 1987 (Anonymous). The purpose of this communication is to describe the procedures used by FDA to develop the final order, to discuss certain major issues that arose during its development, and to answer several questions that have arisen subsequently.     

Perceptions concerning research integrity and the practice of data audit in the biotechnology industry

A survey was conducted in order to evaluate the responses of biotechnology executives concerning their perceptions of the frequency of questionable R & D studies performed in their companies and to assess the extent to which their companies voluntarily conducted data audits. Data audit was found to be commonly practiced on a voluntary basis by biotechnology companies, in contrast to its almost lack of practice by universities. However, public companies were more likely to practice data auditing than privately held companies. Moreover, the likelihood that managers suspected or detected questionable studies in their companies was significantly increased if the company practiced data auditing.     

食品安全问题的比较分析——基于制度、道德、农村基础比较上的讨论

食品安全问题引发了人们各种各样的思考,有的认为是监管制度不健全,有的认为是道德的沦丧,也有的认为是农村的破败,文章对各种观点在中西比较的基础上进行分析,探究食品安全问题频发的根源。     

论当代国家文化安全问题

冷战结束后,时代的主题逐渐过渡为和平与发展。在新的国际形势下,保卫好国家文化安全,就相当于打胜了一场不见硝烟的战争。虽然当下我们的文化安全面临着内在和外部的压力,存在着种种问题,受到了方方面面的挑战,但是随着我们对这一问题关注度的提高,其解决也呈现出多种途径,未来还有很多工作要做,这不仅仅是保持乐观的问题。     

Auditing biochemical research data: A case study

There is little documentation in the literature of how to conduct a data audit of laboratory research. The purpose of such an audit is to verify the extent to which the published data agree with the corresponding laboratory notebook data and whether the data thus examined appear to be sufficient to justify the published conclusions. A case study is presented, which demonstrates a step by step approach towards conducting a data audit of a published research study.     

A randomized,double-blind,placebo-controlled trial of testosterone gel on body composition and health-related quality-of-life in men with hypogonadal to low-normal levels of serum testosterone and symptoms of androgen deficiency over 6 months with 12 months open-label follow-up

Introduction: The clinical significance of low to low-normal testosterone (T) levels in men remains debated. Aim: To analyze the effects of raising serum T on lean body mass (LBM), fat mass (FM), total body mass, and health-related quality-of-life (HRQoL). Methods: Randomized, double-blind, placebo-controlled study. Men, aged 50–80 years, with serum total T<15 nmol/L and bioavailable T < 6.68 nmol/L, and a Aging Males’ Symptoms (AMS) total score >36, received 6 months treatment with transdermal 1% T gel (5–7.5?mg/day; n =183) or placebo gel (n =179), followed by 12 months open-label with T in all. Results: After 6 months, LBM increased in T- treated patients by 1.28?±?0.15?kg (mean ± SE) and FM decreased by 1.16?±?0.16?kg, with minor changes with placebo (LBM +0.02?±?0.10?kg and FM ?0.14?±?0.12?kg; all p < 0.001, T group vs. placebo). Changes were largely similar across subgroups of age, baseline total testosterone, and baseline BMI. Total HRQoL improved compared with placebo (p < 0.05, T group vs. placebo). Conclusions: Six months 1% T gel improved body composition and HRQoL in symptomatic men with low to low-normal T, with further improvements over the following 12 months.     

危害食品安全刑事案件具体法律应用问题研究

食品安全事故频发，保障食品安全已引起社会广泛关注。刑法作为保障食品安全的最后一道屏障，由于其对危害食品安全犯罪的定性不当、保护范围较窄、保护滞后等问题，有大量危害食品安全犯罪案件未进入司法程序，凸显了刑法在惩处食品安全犯罪行为过程中的乏力，也在一定程度上纵容了危害食品安全的犯罪行为。应借鉴美国立法，完善我国危害食品安全犯罪刑事立法，形成严密的刑事立法体系，克服危害食品安全犯罪在刑法规制上的不足。